ea0037gp.09.04 | Nuclear receptors and signalling | ECE2015
Mandic Maja
, Glisic Sanja
, Pedersen Christina
, Veljkovic Nevena
, Nohr Jane
, Vrecl Milka
Evidences for a functional link between insulin receptor (IR) and β2-adrenergic receptor (β2AR) exist in the mouse heart and in retina and are correlated with the cardiovascular dysfunction under insulin-resistant states1 and a diabetic retinopathy phenotype2. In our recent study we showed that i) IR coexpression reduced β2AR surface expression and accelerated its internalization, ii) provided evidence for d...